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Agency Substance Abuse and Mental Health Services Administration Acronym SAMHSA Hierarchy Department of Health and Human Services. Docs Statistical Data; Statistical Publications; Fact Sheets; Miscellaneous Documents URL http://www.samhsa.gov/ Notes SAMHSA is the Federal agency charged with improving the quality and availability of prevention, treatment, and rehabilitation services in order to reduce illness, death, disability, and cost to society resulting from substance abuse and mental illnesses. Subjects MENTAL HEALTH SUBSTANCE ABUSE